Activated PMN exosomes are pathogenic entities that cause destruction in the COPD lung

Researchers have found a novel, pathogenic entity that is a fundamental link between chronic inflammation and tissue destruction in lungs of patients with COPD. These exosomes from activated neutrophils caused COPD damage when they were instilled into the lungs of healthy mice. Remarkably, neutrophil…

Experimental findings support a connection between mucins in the lung and pulmonary fibrosis

A team of investigators has identified a connection between mucus in the small airways and pulmonary fibrosis.

Can scientists change mucus to make it easier to clear, limiting harm to lungs?

For people with conditions such as cystic fibrosis and COPD, mucus can get too thick and sticky; coughing alone can’t clear it. Infections develop, leading to severe chronic disease and early death. Now, for the first time, scientists have shown why coughing often cannot…

Mucus, cough and chronic lung disease

As a cold ends, a severe mucus cough starts. Sound familiar? Two studies now give explanations: First, crucial mechanisms of the mucus in both diseased and healthy airways; second, what happens in such chronic lung diseases as cystic fibrosis and chronic obstructive pulmonary disease…

Common genetic link in lung ailments

An international research team has identified a genetic connection between rheumatoid arthritis-associated interstitial lung disease and idiopathic pulmonary fibrosis.

Benzodiazepines in patients with COPD and PTSD may increase suicide risk

Long-term use of benzodiazepine medications in patients with chronic obstructive pulmonary disease, or COPD, as well as posttraumatic stress disorder (PTSD) may lead to increased suicide risk, according to a new study.

Cooking with wood or coal is linked to increased risk of respiratory illness and death

Burning wood or coal to cook food is associated with increased risk of hospitalization or dying from respiratory diseases.

People with COPD suffer fewer lung-related problems when treated with targeted lung denervation

First results from a clinical trial of a procedure to open obstructed airways in patients with chronic obstructive pulmonary disease (COPD) have shown that it significantly reduces problems associated with the disease and is safe.

Inhaled steroids may increase risk of nontuberculous mycobacteria lung infections

Patients using inhaled steroids to control asthma and other breathing problems may be at greater risk for developing nontuberculous mycobacteria (NTM) lung infections, according to new research.

Testosterone replacement therapy may slow the progression of COPD

Testosterone replacement therapy may slow disease progression of chronic obstructive pulmonary disease, according to new research.