Category: Lung Disease News

A previously validated blood gene profile that predicts idiopathic pulmonary fibrosis mortality was repurposed to assess the likelihood of COVID-19 survival, a new study reports, Source

Researchers have discovered that the use of a common antibiotic, doxycycline, in combination with TB drug treatment, reduces the size of lung cavities and accelerates markers of lung recovery. This was done in a trial with 30 pulmonary tuberculosis patients. Source

Nanodecoys made from human lung spheroid cells (LSCs) can bind to and neutralize SARS-CoV-2, promoting viral clearance and reducing lung injury in a macaque model of COVID-19. By mimicking the receptor that the virus binds to rather than targeting the virus itself, nanodecoy therapy could remain effective against emerging variants of the virus. Source

New research indicates that there are four molecular subtypes of bronchiolitis — the most common lung infection in infants. Children with different subtypes face different risks of later developing asthma. Source

Researchers report that Elovanoids, bioactive chemical messengers made from omega-3 very-long-chain polyunsaturated fatty acids, may block the virus that causes COVID-19 from entering cells and protect the air cells (alveoli) of the lung. Source

Researchers have shown that even after lung tissue has been damaged, it may be possible to reverse fibrosis and promote tissue repair through treatment with microgel-coated mesenchymal stromal cells. Source

When we inhale isolated coronavirus particles, more than 65 percent reach the deepest region of our lungs, new research has discovered, and more of these aerosols reach the right lung than the left. Source

Scientists have found how platelets interacting with white blood cells contribute to the resolution of bacterial lung inflammation in mice. The results may help in the search for therapies to specifically regulate inflammation. Source

The findings dash hopes that antimicrobials would benefit patients with life-threatening idiopathic pulmonary fibrosis. The trial, however, will still benefit the battle against the deadly lung disease, the researchers say. Source

A small molecule STING agonist was highly protective against the virus that causes COVID-19 and likely other coronaviruses, researchers have found. Source