Lung ultrasound shows duration, severity of coronavirus disease (COVID-19)

A new study found that lung ultrasound was highly sensitive for detecting abnormalities in patients with coronavirus disease (COVID-19), with B-lines, a thickened pleural line, and pulmonary consolidation the most commonly observed features. Additionally, the authors found that lung ultrasound features can be used to reflect both the infection duration and disease severity. Source

Cystic fibrosis: Why so many respiratory complications?

Cystic fibrosis causes severe respiratory and digestive disorders. Despite considerable therapeutic advances, this disease still reduces life expectancy, in particular due to life-threatening respiratory infections. Scientists have now discovered the reason for this large number of lung infections: a protein, Vav3. Source

Study identifies unique cells that may drive lung fibrosis

This is one of the first comprehensive looks at lung cells using a technology called single-cell RNA sequencing. Instead of examining a mash-up of many cells from a tissue sample, single-cell sequencing allowed researchers in this study to closely examine the individual cells that make up the lungs; to identify their function, and ultimately understand the molecular changes that may be driving the disease. Source

How targeting killer T cells in the lungs could lead to immunity against respiratory viruses

A significant site of damage during COVID-19 infection is the lungs. Understanding how the lungs’ immune cells are responding to viral infections could help scientists develop a vaccine. Now, a team of researchers has discovered that the cells responsible for long-term immunity in the lungs can be activated more easily than previously thought. The insight could aid in the development of universal vaccines for influenza and the novel coronavirus. Source