Reprogramming immune cells to reduce inflammation, promote tissue repair

A new study suggests that macrophage programming is more complex than previously thought. Source

Blood clots and lung injuries found in patients who have died of COVID-19

A new post-mortem study of patients who have died from COVID-19 found severe damage to the lungs and signs of blood clotting in major organs. Source

Dilated blood vessels in the lung may explain low oxygen levels in severe cases of COVID-19

A new pilot study suggests that COVID-19 is causing significant dilation of the blood vessels of the lung, specifically the capillaries. Source

Team creates better tool to aid COVID-19 diagnosis

A radiologist and an evolutionary anatomist have teamed up to show the same techniques used for research on reptile and bird lungs can be used to help confirm the diagnosis of COVID-19 in patients. Their paper demonstrates that 3D models are a strikingly clearer method for visually evaluating the distribution of COVID-19-related infection in the respiratory system. Source

Oxygen therapy harms lung microbiome in mice

A new mouse study hints that oxygen therapy may have unintended consequences via an unexpected source — the microbiome. Source

Heavier smoking linked to skyrocketing health risks

Each cigarette smoked a day by heavier smokers increases the risk of contracting some diseases by more than 30 per cent, according to a new study. Source

COVID-19: The virus and the vasculature

In severe cases of COVID-19, the infection can lead to obstruction of the blood vessels in the lung, heart and kidneys. Researchers have now shown that activated immune cells and blood platelets play a major role in these pathologies. Source

COVID-19 vaccine shows promise in mouse studies

A new study has found that the investigational vaccine known as mRNA-1273 protected mice from infection with SARS-CoV-2, the virus that causes COVID-19. Source

Assembly within the tumor center

Number of macrophages in tumor tissue enables prognosis of lung tumor progression. Source

Blood-thinner with no bleeding side-effects is here

Scientists have developed a synthetic blood-thinner that, unlike all others, doesn’t cause bleeding side-effects. The highly potent, highly selective, and highly stable molecule can suppress thrombosis while letting blood clot normally following injury. Source