Researchers develop algorithm to find possible misdiagnosis

Researchers have developed an algorithm that can identify patients who may have been wrongly diagnosed. With the help of digital disease history, the algorithm is able to register disease trajectories that differ so much from normal trajectories that there may be a misdiagnosis. The algorithm has been developed on the basis of data from several hundreds of thousands of COPD patients. Source

Sophisticated lung-on-chip created

Researchers have developed a second-generation lung-on-chip model with life-size dimension alveoli in a stretchable membrane, made of purely biological material. The new model reproduces key aspects of the lung tissue architecture not found in previous lungs-on-chip. This opens up new possibilities for basic pneumological research, understanding lung pathologies, drug screening and precision medicine. Source

Using Artificial Intelligence to prevent harm caused by immunotherapy

Until recently, researchers and oncologists had placed lung cancer patients into two broad categories: those who would benefit from immunotherapy, and those who likely would not. Now, researchers, using artificial intelligence (AI) to analyze simple tissue scans, say they have discovered biomarkers that could tell doctors which lung cancer patients might actually get worse from immunotherapy. Source

Hyaluronan is effective in treating chronic lung disease

Researchers found that inhaling unfragmented hyaluronan improves lung function in patients suffering from severe exacerbation of chronic obstructive pulmonary disease (COPD). Hyaluronan, a sugar secreted by living tissue that acts as a scaffold for cells, is also used in cosmetics as a skin moisturizer and as a nasal spray to moisturize lung airways. Utilized as a treatment, hyaluronan decreased the number of days in the hospital. Source

Light pollution linked to preterm birth increase

Scientists conducted the first study to examine the fetal health impact of light pollution based on a direct measure of skyglow, an important aspect of light pollution. Using an empirical regularity discovered in physics, called Walker’s Law, a team found evidence of reduced birth weight, shortened gestational length and preterm births. Source