How the power of mathematics can help assess lung function

Researchers have developed a new computational way of analyzing X-ray images of lungs, which could herald a breakthrough in the diagnosis and assessment of chronic obstructive pulmonary disease (COPD) and other lung diseases. Source

Occupational exposures linked with increased risk of COPD

A study with more than 3,300 participants in 12 countries has established a relationship between occupational exposure to biological dusts, gases, fumes and pesticides and COPD. The researchers did a follow-up of the participants 20 years after the first assessment. Source

COPD-associated inflammation halted in model experiment

Chronic obstructive pulmonary disease, or COPD for short, is believed to be the third most common cause of death worldwide. However, because the underlying mechanism is still largely unknown, today’s treatments can only slow progression of the disease. Scientists have now reported a previously unknown pathogenic mechanism, which they have already been able to prevent in the laboratory. Source

Formidable duo: Protective effect of CD9 and CD81 in COPD and accelerated aging

Chronic obstructive pulmonary disease (COPD) is a disease of accelerated lung aging, but the mechanism remains unclear. Researchers studied the aging-like phenotype and its underlying mechanisms in a COPD mouse model. Double deletion of tetraspanins CD9 and CD81 in epithelial cells downregulated expression of the protein SIRT. As SIRT1 is a key molecule that protects against various lifestyle-related diseases and aging, these tetraspanins may serve as novel therapeutic targets for COPD and aging. Source

Position statement: Avoid using medical marijuana to treat sleep apnea

Medical cannabis and synthetic marijuana extracts should not be used for the treatment of obstructive sleep apnea, according to a position statement from the American Academy of Sleep Medicine. Source

Almost 100 million adults have COPD in China

Chronic obstructive pulmonary disease (COPD) is widespread in China with 8.6 percent of the country’s adult population — almost 100 million people — suffering from the chronic lung disease, according to a new study. The study, which provided lung-function screenings for more than 50,990 participants, is the largest survey of COPD across age groups ever conducted in China. Source

Three-quarters of COPD cases are linked to childhood risk factors that are exacerbated in adulthood

Three-quarters of chronic obstructive pulmonary disease (COPD) cases have their origins in poor lung function pathways beginning in childhood. These pathways are associated with exposures in childhood, and amplified by factors in adulthood, according to a cohort study. While smoking remains the biggest risk factor for COPD, the study demonstrates that childhood illnesses (such as asthma, bronchitis, pneumonia, allergic rhinitis, eczema) and exposures to parental smoking are also linked to the disease. Source

Sleep deficiency increases risk of a motor vehicle crash

Individuals may be unaware of their degree of impairment from sleep deficiency, which raises the question of whether these individuals are at an increased risk of motor vehicle crash. Source

Sleep apnea study finds male-female differences in cerebral cortex thickness, symptoms

Researchers examined clinical records and magnetic resonance imaging brain scans of patients who were recently diagnosed with sleep apnea, and discovered several apparent connections between thinning of the brain’s cerebral cortex and apnea symptoms. Source

Restoring lipid synthesis could reduce lung fibrosis

Increasing the body’s ability to produce lipids in the lungs after damage prevents the progression of pulmonary fibrosis in preliminary studies. Source