Identical signs of brain damage in sleep apnea and Alzheimer’s

New research shows damage in the brain starts in the same place and spreads in the same way in sleep apnea, as in Alzheimer’s disease. The study is the first to find Alzheimer’s-like amyloid plaques in the brains of people with clinically-verified obstructive sleep apnea, a condition that affects more than 936 million people worldwide. Source

A step toward helping patients breathe deeply

Researchers report that a protein called TL1A drives fibrosis in several mouse models, triggering tissue remodeling, and making it harder for lungs and airways to function normally. Source

New vulnerability found in lung squamous cancer may facilitate drug targeting

New cancer research shows the potential for targeting a specific circular RNA, known as CDR1as, to attack lung squamous cell cancer. Source

Loneliness levels high during COVID-19 lockdown

During the initial phase of COVID-19 lockdown, rates of loneliness among people in the UK were high and were associated with a number of social and health factors, according to a new study. Source

Gut microbiome plays important role in sleep regulation

Obstructive sleep apnea (OSA) affects more than one billion people worldwide. Evidence suggests OSA can alter the gut microbiome (GM) and may promote OSA-associated co-morbidities, including diabetes, hypertension and cognitive problems. Researchers have discovered how OSA-related sleep disturbances affect the gut microbiome in mice and how transplanting those gut bacteria into other mice can cause changes to sleep patterns in the recipient mice. Source

Weighted blankets can decrease insomnia severity

Weighted blankets are a safe and effective intervention in the treatment of insomnia, according to researchers who found that insomnia patients with psychiatric disorders experienced reduced insomnia severity, improved sleep and less daytime sleepiness when sleeping with a weighted chain blanket. Source

The hypnotic potential of thalidomide

Researchers demonstrate that the hypnotic and teratogenic effects of thalidomide are separable. Source

Insomnia treatment offers relief

Insomnia causing sleepless nights, daytime fatigue and poor health outcomes is a cycle worth busting, experts say, with depression, anxiety and stress a common co-occurrence. A study of more than 450 insomnia patients in Australia has confirmed some positive results for such patients with insomnia. Source

Stroke scans could reveal COVID-19 infection

New research has found that COVID-19 may be diagnosed on the same emergency scans intended to diagnose stroke. Source

People react better to both negative and positive events with more sleep

New research finds that after a night of shorter sleep, people react more emotionally to stressful events the next day — and they don’t find as much joy in the good things. This has important health implications: previous research shows that being unable to maintain positive emotions in the face of stress puts people at risk of inflammation and even an earlier death. Source